PDK-1 Products

Antibodies
PDK-1 Antibody (SD204-9)
PDK-1 Antibody (SD204-9)
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Monoclonal
PDK-1 Antibody (650308) [Unco ...
PDK-1 Antibody (650308) [Unconjuga...
MAB864
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
PDK-1 Antibody
PDK-1 Antibody
H00005170-B01P
Species: Hu, Mu
Applications: WB, PLA
Host: Mouse Polyclonal
Lysates
PDK-1 Overexpression Lysate
PDK-1 Overexpression Lysate
NBL1-14260
Species: Hu
Applications: WB
PDK-1 Overexpression Lysate
PDK-1 Overexpression Lysate
NBL1-14259
Species: Hu
Applications: WB
Proteins
Recombinant Human Active PDK- ...
Recombinant Human Active PDK-1 Pro...
864-KS
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
PDK-1 Recombinant Protein Ant ...
PDK-1 Recombinant Protein Antigen
NBP2-48631PEP
Species: Hu
Applications: AC
PDK-1 Recombinant Protein Ant ...
PDK-1 Recombinant Protein Antigen
NBP2-56546PEP
Species: Hu
Applications: AC

Description

PDK-1 (3-phosphoinositide-dependent protein kinase, gene name PDPK1) is a 58 -68 kDa, 556 amino acid (aa) monomeric protein of the AGC serine/threonine kinase family. It is activated by phosphorylation in the presence of PtdIns(3,4,5) P3 or PtdIns(3,4) P2. Akt, S6 kinases, PKA and PKC-zeta are reported PDK-1 substrates. Through Akt, PDK-1 mediates many of the intracellular actions of insulin. Within the region used as an immunogen, human PDK-1 shares 98% aa identity with mouse and rat PDK-1. One reported isoform has an alternate start site at aa 50, while another lacking aa 238-263 is predicted to be catalytically inactive.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 5170
Alternate Names
  • PDK1
  • PDPK2
  • PDPK2P
  • 3-phosphoinositide-dependent protein kinase 1
  • 3-phosphoinositide-dependent protein kinase 2 pseudogene
  • PkB kinase like gene 1

Research Areas for PDK-1

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Cancer
Cytoskeleton Markers
Hypoxia
Lipid and Metabolism
mTOR Pathway
Phospho-Specific
Protein Kinase
Signal Transduction

PTMs for PDK-1

Learn more about PTMs related to PDK-1.

Phosphorylation
Cleavage
Acetylation
Dephosphorylation
Methylation

Bioinformatics Tool for PDK-1

Discover related pathways, diseases and genes to PDK-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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