PDGF-C Products

Antibodies
PDGF-C Antibody
PDGF-C Antibody
AF1447
Species: Mu
Applications: WB, IHC, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
PDGF-C Antibody
PDGF-C Antibody
AF1560
Species: Hu
Applications: WB, IHC, Neut
Host: Goat Polyclonal
PDGF-C Antibody (184129)
PDGF-C Antibody (184129)
MAB1447
Species: Mu
Applications: WB
Host: Rat Monoclonal
Lysates
PDGF-C Overexpression Lysate ...
PDGF-C Overexpression Lysate (Dena...
H00056034-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human PDGF-C Prot ...
Recombinant Human PDGF-C Protein
H00056034-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human PDGF-C Prot ...
Recombinant Human PDGF-C Protein
H00056034-P01
Species: Hu
Applications: WB, ELISA, PA
PDGF-C Recombinant Protein An ...
PDGF-C Recombinant Protein Antigen
NBP1-83935PEP
Species: Hu
Applications: AC
RNAi
PDGF-C RNAi
PDGF-C RNAi
H00056034-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

PDGFC, also known as Platelet-derived growth factor C, has 3 isoforms, a 345 amino acid isoform that is 39 kDa, a 282 amino acid isoform that is 32 kDa and a 167 amino acid isoform that is 19 kDa, expressed in the fallopian tube, vascular smooth muscle cells in kidney, breast and colon and in visceral smooth muscle of the gastrointestinal tract and retinal pigment epithelia; plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis, wound healing, represents potent mitogen for cells of mesenchymal origin, induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis, can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix. This protein is being studied for its involvement in mesangial proliferative glomerulonephritis, proliferative glomerulonephritis, glomerulonephritis, brain cancer, prostate carcinoma, nephropathy, prostatitis, prostate cancer, atherosclerosis, retinitis, melanoma, and carcinoma. The protein has been linked to the cytoskeleton remodeling role of PDGFs in cell migration, development PDGF signaling via MAPK cascades, release of novel PDGFs as latent factors, signal transduction, signaling by PD, focal adhesion, gap junction, regulation of actin cytoskeleton, prostate cancer, and melanoma GF pathways where it interacts with PDGFRB, PDGFRA, PLAT, PLAU, PLAUR, EGFR, ERBB2, FGFR1, FLT1, and FLT4 proteins.

Bioinformatics

Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 56034
Alternate Names
  • fallotein
  • Fallotein
  • VEGF-E
  • secretory growth factor-like protein
  • PDGF-C
  • platelet-derived growth factor C
  • SCDGFSpinal cord-derived growth factor
  • FALLOTEIN
  • platelet derived growth factor C

Research Areas for PDGF-C

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

PTMs for PDGF-C

Learn more about PTMs related to PDGF-C.

Phosphorylation
Cleavage

Bioinformatics Tool for PDGF-C

Discover related pathways, diseases and genes to PDGF-C. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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