PDE1A Products

Antibodies
PDE1A Antibody (7D5)
PDE1A Antibody (7D5)
NBP2-46355
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
PDE1A Antibody
PDE1A Antibody
NBP1-86009
Species: Hu, Mouse
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PDE1A Antibody
PDE1A Antibody
NBP1-51996
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Antibody Pairs
PDE1A Antibody Pair
PDE1A Antibody Pair
H00005136-PW1
Species: Hu
Applications: WB, IP
Lysates
PDE1A Overexpression Lysate ( ...
PDE1A Overexpression Lysate (Denat...
H00005136-T01
Species: Hu
Applications: WB
PDE1A Overexpression Lysate ( ...
PDE1A Overexpression Lysate (Native)
NBL1-14214
Applications: WB
Proteins
PDE1A Partial Recombinant Pro ...
PDE1A Partial Recombinant Protein
H00005136-Q01
Species: Hu
Applications: WB, ELISA, PA
PDE1A Recombinant Protein
PDE1A Recombinant Protein
H00005136-P01
Species: Hu
Applications: WB, ELISA, PA
PDE1A Recombinant Protein Ant ...
PDE1A Recombinant Protein Antigen
NBP1-86009PEP
Species: Hu
Applications: AC

Description

PDE1A, a variant of PDE1, is a Ca2+-calmodulin-stimulated phosphodieterase (PDE) preferentially hydrolyzing cGMP. Cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases. In mammals at least 11 different families of PDEs can be discriminated (PDE1-11) based on their kinetic properties and inhibition to various pharmacological agents. Three different PDE1 genes have been identified (PDE1A, B, and C). PDE1A and PDE1B have higher affinity for cGMP than for cAMP, whereas PDE1C has high affinity for both cAMP and cGMP. The PDE1A gene family includes various proteins that differ from each other at amino and carboxy termini of the protein.

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 5136
Alternate Names
  • MGC26303
  • EC 3.1.4
  • HSPDE1A
  • phosphodiesterase-1A
  • HCAM1
  • calmodulin-dependent phosphodiesterase
  • 3'-5' cyclic nucleotide phosphodiesterase
  • calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase
  • EC 3.1.4.17
  • calcium/calmodulin-dependent 3'-5'-cyclic nucleotide phosphodiesterase 1A
  • hCam-1
  • 61 kDa Cam-PDE
  • Cam-PDE 1A
  • phosphodiesterase 1A, calmodulin-dependent

PTMs for PDE1A

Learn more about PTMs related to PDE1A.

Phosphorylation
Biotinylation

Bioinformatics Tool for PDE1A

Discover related pathways, diseases and genes to PDE1A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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