PDCD4 Products

Antibodies
PDCD4 Antibody
PDCD4 Antibody
NBP1-83302
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
PDCD4 Antibody
PDCD4 Antibody
AF7019
Species: Hu
Applications: IHC, ICC
Host: Sheep Polyclonal
PDCD4 Antibody
PDCD4 Antibody
NBP1-76738
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PDCD4 Overexpression Lysate ( ...
PDCD4 Overexpression Lysate (Denat...
H00027250-T01
Species: Hu
Applications: WB
PDCD4 Overexpression Lysate ( ...
PDCD4 Overexpression Lysate (Native)
NBP2-07331
Applications: WB
Proteins
PDCD4 Recombinant Protein Ant ...
PDCD4 Recombinant Protein Antigen
NBP1-83301PEP
Species: Hu
Applications: AC
PDCD4 Recombinant Protein Ant ...
PDCD4 Recombinant Protein Antigen
NBP1-83302PEP
Species: Hu
Applications: AC
PDCD4 Recombinant Protein
PDCD4 Recombinant Protein
NBC1-18506
Species: Hu
Applications: PAGE

Description

Programmed cell death 4 (Pdcd4) is a novel tumor suppressor. Pdcd4 directly inhibits the helicase activity of eukaryotic translation initiation factor 4A (eIF4A), a component of the translation initiation complex. Pdcd4 also suppresses the transactivation of activator protein-1 (AP-1)-responsive promoters by c-Jun. Pdcd4 contains two Akt phosphorylation sites, one at Ser67 and the other at Ser457. The phosphorylation of Pdcd4 by Akt causes nuclear translocation of Pdcd4 and a significant decrease in the ability of Pdcd4 to interfere with the transactivation of AP-1 responsive promoters by c-Jun.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 27250
Alternate Names
  • MGC33046
  • Nuclear antigen H731-like
  • Protein 197/15a
  • programmed cell death protein 4
  • Neoplastic transformation inhibitor protein
  • H731nuclear antigen H731
  • MGC33047
  • programmed cell death 4 (neoplastic transformation inhibitor)

Research Areas for PDCD4

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Phospho-Specific

Bioinformatics Tool for PDCD4

Discover related pathways, diseases and genes to PDCD4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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