PCYT2 Products

Description

ECT (ethanolamine phosphate cytidyltransferase) is an important regulatory enzyme in the pathway for phosphatidylethanolamine (PE) biosynthesis. PE functions in cell signalling, membrane fusion, platelet activation, and cell cycle progression. Specialized forms of PE exist as plasmologens, natural cannabinoid anadimade, and glycosylated PE. The ECT enzyme acts in the second of three catalysis steps to produce CDP-ethanolamine from phosphoethanolamine (P-Etn). Study of ECT could help determine the role of plasmologens in disease, specifically lipid disorders such as peroxisomal diseases as well as neuronal degeneration associated with Alzheimer's disease.

Bioinformatics

Uniprot	NP_002852 Human NP_002852.1 Human Q99447 Human
Product By Gene ID	5833
Alternate Names	CTP:phosphoethanolamine cytidylyltransferase EC 2.7.7 EC 2.7.7.14 ET ethanolamine-phosphate cytidylyltransferase phosphate cytidylyltransferase 2, ethanolamine Phosphorylethanolamine transferase