PCBP2 Products

Antibodies
PCBP2 Antibody (5F12)
PCBP2 Antibody (5F12)
H00005094-M07
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
PCBP2 Antibody
PCBP2 Antibody
NBP2-19715
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
PCBP2 Antibody
PCBP2 Antibody
NBP1-83241
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
PCBP2 Antibody Pair
PCBP2 Antibody Pair
H00005094-PW1
Species: Hu
Applications: WB, IP
Lysates
PCBP2 Overexpression Lysate ( ...
PCBP2 Overexpression Lysate (Native)
NBP2-07800
Applications: WB
PCBP2 Overexpression Lysate ( ...
PCBP2 Overexpression Lysate (Native)
NBP2-09812
Applications: WB
PCBP2 Overexpression Lysate ( ...
PCBP2 Overexpression Lysate (Native)
NBL1-14143
Applications: WB
Proteins
PCBP2 Recombinant Protein
PCBP2 Recombinant Protein
H00005094-P01
Species: Hu
Applications: WB, ELISA, PA
PCBP2 Partial Recombinant Pro ...
PCBP2 Partial Recombinant Protein
H00005094-Q01
Species: Hu
Applications: WB, ELISA, PA
PCBP2 Recombinant Protein Ant ...
PCBP2 Recombinant Protein Antigen
NBP1-83241PEP
Species: Hu
Applications: AC
RNAi
PCBP2 RNAi
PCBP2 RNAi
H00005094-R01V
Species: Hu
Applications: WB, RNAi SP
PCBP2 RNAi
PCBP2 RNAi
H00005094-R02
Species: Hu
PCBP2 RNAi
PCBP2 RNAi
H00005094-R01
Species: Hu

Description

PCBP2 is encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of only three have been characterized to date.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 5094
Alternate Names
  • Alpha-CP2
  • Heterogeneous nuclear ribonucleoprotein E2
  • heterogenous nuclear ribonucleoprotein E2
  • poly(rC)-binding protein 2
  • alpha-CP2
  • hnRNP-E2
  • MGC110998
  • HNRPE2
  • hnRNP E2
  • poly(rC) binding protein 2

PTMs for PCBP2

Learn more about PTMs related to PCBP2.

Cleavage
Phosphorylation
Reduction
Hydroxylation

Bioinformatics Tool for PCBP2

Discover related pathways, diseases and genes to PCBP2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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