Species: Hu, Mu, Rt, Ca, Xp
Applications: WB, Simple Western, ICC/IF, IHC, IP, ChIP, Single-Cell Western
Host: Rabbit Polyclonal
Species: Hu, Mu, Pm, Pm
Applications: WB, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Pm, Pm
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described.
Bioinformatics
Uniprot |
Human Human Human Human Human Human |
Product By Gene ID |
7849 |
Alternate Names |
- paired box 8
- paired box gene 8
- paired box protein Pax-8
- paired domain gene 8
|
Research Areas for PAX8
Find related products by research area and learn more about each of the different research areas below.
Cancer