P2Y2 Products

Description

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID	5029
Alternate Names	ATP receptor HP2U MGC20088 MGC40010 P2RU1 P2RY2 P2U nucleotide receptor P2U purinoceptor 1 P2U P2U1 P2UP2UR P2Y purinoceptor 2 P2Y2 P2Y2P2Y2R P2Y2R purinergic receptor P2Y, G-protein coupled, 2 purinergic receptor P2Y2 Purinergic receptor purinoceptor P2Y2

Research Areas for P2Y2

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GPCR
Neuroscience

Related P2Y2 Blog Posts

Check out the latest blog posts on P2Y2.

P2Y2 (P2Y purinoceptor 2, ATP receptor) The protein P2Y2 is a G-protein coupled metabotropic receptor that belongs to a larger family consisting of several receptor subtypes that each has a different pharmacological selectivity for various adenosine and uridine nucleotides. (This selecti...    Read more.

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