P11 Products

Antibodies
P11 Antibody
P11 Antibody
NBP1-82458
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
P11 Antibody
P11 Antibody
NB100-40907
Species: Rt
Applications: IHC, IHC-P
Host: Chicken Polyclonal
Lysates
P11 Overexpression Lysate (Na ...
P11 Overexpression Lysate (Native)
NBP2-11464
Applications: WB
Proteins
P11 Partial Recombinant Prote ...
P11 Partial Recombinant Protein
H00008909-Q01
Species: Hu
Applications: WB, ELISA, PA
P11 Recombinant Protein Antig ...
P11 Recombinant Protein Antigen
NBP1-82458PEP
Species: Hu
Applications: AC

Description

p11 increases localization of 5-HT1B receptors at the cell surface. It is increased in rodent brains by antidepressants or electroconvulsive therapy, but decreased in an animal model of depression and in brain tissue from depressed patients. Overexpression of p11 increases 5-HT1B receptor function in cells and recapitulates certain behaviors seen after antidepressant treatment in mice. p11 knockout mice exhibit a depression-like phenotype and have reduced responsiveness to 5-HT1B receptor agonists and reduced behavioral reactions to an antidepressant.

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 8909
Alternate Names
  • EC 3.1
  • Protein endoU
  • poly(U)-specific endoribonuclease
  • Placental protein 11
  • MGC133268
  • PRSS26
  • P11,26 serine protease
  • PP1122 serine protease
  • Uridylate-specific endoribonuclease
  • endonuclease, polyU-specific

Diseases related to P11

Discover more about diseases related to P11.

Acidosis
Proximal Renal Tubular Acidosis
Severe Acute Respiratory Syndrome
Renal Tubular Acidosis
Glaucoma

Pathways for P11

View related products by pathway and learn more about each of the pathways below.

Transport
Amino Acid Transport
Cell Killing
Cell Death
Ion Transport
Fluid Transport
Neutral Amino Acid Transport

PTMs for P11

Learn more about PTMs related to P11.

Glycosylation

Bioinformatics Tool for P11

Discover related pathways, diseases and genes to P11. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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