ORC1 Products

Antibodies
ORC1 Antibody
ORC1 Antibody
NBP2-24600
Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
ORC1 Antibody
ORC1 Antibody
NBP1-05957
Species: Hu
Applications: WB, IP, PLA
Host: Rabbit Polyclonal
ORC1 Antibody
ORC1 Antibody
NBP1-83184
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
ORC1 Overexpression Lysate (D ...
ORC1 Overexpression Lysate (Denatu...
H00004998-T01
Species: Hu
Applications: WB
ORC1 Overexpression Lysate (N ...
ORC1 Overexpression Lysate (Native)
NBP2-07905
Applications: WB
Proteins
Recombinant Human ORC1 Protei ...
Recombinant Human ORC1 Protein
H00004998-Q01
Species: Hu
Applications: WB, ELISA, PA
ORC1 Recombinant Protein Anti ...
ORC1 Recombinant Protein Antigen
NBP1-83184PEP
Species: Hu
Applications: AC
RNAi
ORC1 RNAi
ORC1 RNAi
H00004998-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. [provided by RefSeq]

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 4998
Alternate Names
  • origin recognition complex, subunit 1 homolog (S. cerevisiae)
  • HS
  • origin recognition complex, subunit 1 (yeast homolog)-like
  • origin recognition complex, subunit 1-like
  • Replication control protein 1
  • origin recognition complex, subunit 1 homolog
  • HSORC1
  • ORC1Lorigin recognition complex subunit 1
  • PARC1origin recognition complex 1
  • origin recognition complex, subunit 1-like (yeast)
  • origin recognition complex, subunit 1

Research Areas for ORC1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Core ESC-Like Genes
DNA Repair
Stem Cell Markers

Bioinformatics Tool for ORC1

Discover related pathways, diseases and genes to ORC1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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