NSUN2 Products

Antibodies
NSUN2 Antibody
NSUN2 Antibody
NBP1-86878
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
NSUN2 Antibody
NSUN2 Antibody
NBP1-82189
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
NSUN2 Antibody
NSUN2 Antibody
NBP1-53052
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
NSUN2 Overexpression Lysate ( ...
NSUN2 Overexpression Lysate (Native)
NBL1-13814
Applications: WB
Proteins
NSUN2 Recombinant Protein Ant ...
NSUN2 Recombinant Protein Antigen
NBP1-82189PEP
Species: Hu
Applications: AC
NSUN2 Recombinant Protein Ant ...
NSUN2 Recombinant Protein Antigen
NBP1-86878PEP
Species: Hu
Applications: AC

Description

Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA) (Brzezicha et al., 2006 [PubMed 17071714]).[supplied by OMIM].

Bioinformatics

Uniprot Human
Human
Product By Gene ID 54888
Alternate Names
  • tRNA methyltransferase 4 homolog
  • EC 2.1.1
  • NOL1/NOP2/Sun domain family member 2
  • tRNA (cytosine-5-)-methyltransferase
  • hTrm4
  • tRNA (cytosine-5-)-methyltransferase NSUN2
  • Substrate of AIM1/Aurora kinase B
  • Myc-induced SUN-domain-containing protein
  • member 2
  • NOL1/NOP2/Sun domain family 2
  • FLJ20303,5-methycytoisine methyltransferase
  • SAKIMisu
  • TRM4MISU
  • EC 2.1.1.29
  • NOP2/Sun domain family, member 2

PTMs for NSUN2

Learn more about PTMs related to NSUN2.

Methylation
Phosphorylation

Bioinformatics Tool for NSUN2

Discover related pathways, diseases and genes to NSUN2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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