NSF Products

Antibodies
NSF Antibody
NSF Antibody
NBP1-87035
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
NSF Antibody (9G7-3)
NSF Antibody (9G7-3)
NBP1-19333
Species: Hu, Mu, Rt, Po, Bv, Ca, Ch, Pm, Rb, Sh
Applications: WB, IHC
Host: Mouse Monoclonal
NSF Antibody
NSF Antibody
NBP1-57536
Species: Mu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Lysates
NSF Overexpression Lysate (De ...
NSF Overexpression Lysate (Denatured)
H00004905-T01
Species: Hu
Applications: WB
NSF Overexpression Lysate (Na ...
NSF Overexpression Lysate (Native)
NBL1-13808
Applications: WB
Proteins
NSF Recombinant Protein
NSF Recombinant Protein
H00004905-P01
Species: Hu
Applications: WB, ELISA, IP, PA
NSF Recombinant Protein Antig ...
NSF Recombinant Protein Antigen
NBP1-87035PEP
Species: Hu
Applications: AC
RNAi
NSF RNAi
NSF RNAi
H00004905-R01
Species: Hu

Description

N ethylmaleimide sensitive factor (NSF) is an ~83 kDa protein (predicted MW) which was initially isolated based on its ability to restore intercisternal Golgi transport to N ethylmaleimide treated membranes. NSF was subsequently discovered to be involved in a variety of membrane fusion events. NSF is an ATPase with two ATP binding domains that are essential for membrane fusion and homo oligomerization. In order to interact with target membranes, NSF requires another set of soluble proteins called Soluble NSF attachment proteins (SNAPs). NSF has been shown to play a prominent role in synaptic vesicle fusion. Together with synaptotagmin and a SNAP, NSF modulates the interaction of SNAP25, VAMP, and syntaxin, in an ATP dependent manner, to form a complex with a sedimentation coefficient of 20 S. This complex may represent an intermediate involved in synaptic vesicle docking and fusion.

Bioinformatics

Uniprot Human
Human
Human
Rat
Product By Gene ID 4905
Alternate Names
  • vesicle-fusing ATPase
  • N-ethylmaleimide-sensitive fusion protein
  • N-ethylmaleimide-sensitive factor-like protein
  • Vesicular-fusion protein NSF
  • EC 3.6.4.6
  • SKD2
  • NEM-sensitive fusion protein
  • N-ethylmaleimide-sensitive factor

Bioinformatics Tool for NSF

Discover related pathways, diseases and genes to NSF. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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