NRIF3 Products

Antibodies
NRIF3 Antibody
NRIF3 Antibody
NBP1-85687
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
NRIF3 Antibody (3F6)
NRIF3 Antibody (3F6)
H00023421-M01
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
NRIF3 Antibody (4H1)
NRIF3 Antibody (4H1)
NBP2-45461
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
Lysates
NRIF3 Overexpression Lysate ( ...
NRIF3 Overexpression Lysate (Native)
NBL1-12074
Applications: WB
Proteins
NRIF3 Recombinant Protein Ant ...
NRIF3 Recombinant Protein Antigen
NBP1-85687PEP
Species: Hu
Applications: AC
NRIF3 Recombinant Protein
NRIF3 Recombinant Protein
NBP2-23143
Species: Hu
Applications: PAGE
RNAi
NRIF3 RNAi
NRIF3 RNAi
H00023421-R01
Species: Hu

Description

Transcription coregulator that can have both coactivator and corepressor functions. Isoform 1, but not other isoforms, is involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion. In contrast, it does not coactivate nuclear receptors for retinoic acid, vitamin D, progesterone receptor, nor glucocorticoid. Acts as a coactivator for estrogen receptor alpha. Acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1. Induces apoptosis in breast cancer cells, but not in other cancer cells, via a caspase-2 mediated pathway that involves mitochondrial membrane permeabilization but does not require other caspases. May also act as an inhibitor of cyclin A-associated kinase. Also acts a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Product By Gene ID 23421
Alternate Names
  • Nuclear receptor-interacting factor 3
  • Beta-3-endonexin
  • Integrin beta-3-binding protein
  • centromere protein R
  • TAP20
  • beta-3-endonexin
  • HSU37139
  • NRIF3CENPRbeta 3 endonexin
  • CENP-R
  • integrin beta 3 binding protein (beta3-endonexin)

Research Areas for NRIF3

Find related products by research area and learn more about each of the different research areas below.

Apoptosis

PTMs for NRIF3

Learn more about PTMs related to NRIF3.

Phosphorylation

Bioinformatics Tool for NRIF3

Discover related pathways, diseases and genes to NRIF3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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