NRIF3 Products

NRIF3 Antibody
NRIF3 Antibody
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
NRIF3 Antibody
NRIF3 Antibody
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
NRIF3 Antibody (3F6)
NRIF3 Antibody (3F6)
Species: Hu
Applications: WB, ELISA, ICC/IF, S-ELISA
Host: Mouse Monoclonal
NRIF3 Overexpression Lysate
NRIF3 Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human NRIF3 His P ...
Recombinant Human NRIF3 His Protein
Species: Hu
Applications: PAGE
NRIF3 Recombinant Protein Ant ...
NRIF3 Recombinant Protein Antigen
Species: Hu
Applications: AC


Transcription coregulator that can have both coactivator and corepressor functions. Isoform 1, but not other isoforms, is involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion. In contrast, it does not coactivate nuclear receptors for retinoic acid, vitamin D, progesterone receptor, nor glucocorticoid. Acts as a coactivator for estrogen receptor alpha. Acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1. Induces apoptosis in breast cancer cells, but not in other cancer cells, via a caspase-2 mediated pathway that involves mitochondrial membrane permeabilization but does not require other caspases. May also act as an inhibitor of cyclin A-associated kinase. Also acts a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex


Uniprot Human
Product By Gene ID 23421
Alternate Names
  • Beta-3-endonexin
  • beta-3-endonexin
  • CENP-R
  • centromere protein R
  • HSU37139
  • integrin beta 3 binding protein (beta3-endonexin)
  • Integrin beta-3-binding protein
  • NRIF3CENPRbeta 3 endonexin
  • Nuclear receptor-interacting factor 3
  • TAP20

Research Areas for NRIF3

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PTMs for NRIF3

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Bioinformatics Tool for NRIF3

Discover related pathways, diseases and genes to NRIF3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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