NMRAL1 Products

Antibodies
Lysates
NMRAL1 Overexpression Lysate
NMRAL1 Overexpression Lysate
NBL1-13693
Species: Hu
Applications: WB
Proteins
Recombinant Human NMRAL1 His ...
Recombinant Human NMRAL1 His Protein
NBP1-98943
Species: Hu
Applications: PAGE
NMRAL1 Recombinant Protein An ...
NMRAL1 Recombinant Protein Antigen
NBP1-83554PEP
Species: Hu
Applications: AC

Description

Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes inintracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and bindsargininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs itsactivity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPHconcentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one moleculeof NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 57407
Alternate Names
  • HSCARGFLJ25918
  • NmrA-like family domain containing 1
  • nmrA-like family domain-containing protein 1
  • SDR48A1
  • short chain dehydrogenase/reductase family 48A, member 1