NLK Products

Description

Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP . Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3

Bioinformatics

Uniprot	AAH64663 Human NM_016231 Human NP_057315 Human
Product By Gene ID	51701
Alternate Names	DKFZp761G1211 EC 2.7.11 EC 2.7.11.24 FLJ21033 LAK1 nemo like kinase nemo-like kinaseserine/threonine-protein kinase NLK Protein LAK1

Research Areas for NLK

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase
Wnt Signaling Pathway