NKIRAS1 Products

Antibodies
NKIRAS1 Antibody (6C11)
NKIRAS1 Antibody (6C11)
NBP2-45858
Species: Hu
Applications: WB, IHC, IF
Host: Mouse monoclonal
NKIRAS1 Antibody
NKIRAS1 Antibody
NBP1-76726
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
NKIRAS1 Overexpression Lysate ...
NKIRAS1 Overexpression Lysate (Nat...
NBL1-13655
Applications: WB
Proteins
NKIRAS1 Recombinant Protein
NKIRAS1 Recombinant Protein
NBP1-99105
Species: Hu
Applications: PAGE
NKIRAS1 Blocking Peptide
NKIRAS1 Blocking Peptide
NBP1-76725PEP
Species: Hu
Applications: AC
NKIRAS1 Peptide
NKIRAS1 Peptide
NBP1-76726PEP
Species: Hu
Applications: AC
RNAi
NKIRAS1 RNAi
NKIRAS1 RNAi
H00028512-R01
Species: Hu

Description

NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. Synthesis of IkBa is autoregulated. IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/a, IKK2/b, and IKK3/g. External stimuli such as tumor necrosis factor or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified. One of the first genes induced following NF-kB activation is IkBa. Recently, two proteins, kB-Ras1 and kB-Ras2 have been identified. These two proteins interact with PEST domains of IkBa and IkBb and decrease their rate of degradation.

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 28512
Alternate Names
  • I-kappa-B-interacting Ras-like protein 1
  • KappaB-Ras1
  • Kappa B-Ras protein 1
  • NF-kappa-B inhibitor-interacting Ras-like protein 1
  • NFKB inhibitor interacting Ras-like protein 1
  • kappa B-ras 1
  • KBRAS1kappaB-Ras1
  • NFKB inhibitor interacting Ras-like 1

Pathways for NKIRAS1

View related products by pathway and learn more about each of the pathways below.

Methylation
Cell Growth

Research Areas for NKIRAS1

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

PTMs for NKIRAS1

Learn more about PTMs related to NKIRAS1.

Methylation

Bioinformatics Tool for NKIRAS1

Discover related pathways, diseases and genes to NKIRAS1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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