NHERF-1 Products

Antibodies
NHERF-1 Antibody
NHERF-1 Antibody
NB300-536
Species: Hu, Mu, Rt, Ca
Applications: WB, IHC, IHC-P, IP, IF
Host: Rabbit Polyclonal
NHERF-1 Antibody
NHERF-1 Antibody
NBP1-84919
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
NHERF-1 Antibody
NHERF-1 Antibody
NBP1-84918
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
NHERF-1 Overexpression Lysate ...
NHERF-1 Overexpression Lysate (Nat...
NBL1-16198
Applications: WB
NHERF-1 Overexpression Lysate ...
NHERF-1 Overexpression Lysate (Den...
H00009368-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human NHERF-1 Pro ...
Recombinant Human NHERF-1 Protein
H00009368-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human NHERF-1 Pro ...
Recombinant Human NHERF-1 Protein
H00009368-Q01
Species: Hu
Applications: WB, ELISA, PA
NHERF-1 Recombinant Protein A ...
NHERF-1 Recombinant Protein Antigen
NBP1-84919PEP
Species: Hu
Applications: AC

Description

EBP 50 [ERM (ezrin-radixin-moesin) binding phosphoprotein of 50 kDa] is a PDZ containing protein that is involved in the linkage of integral membrane proteins to the cytoskeleton. EBP50 contains two tandem PDZ domains followed by a carboxy-terminal sequence that binds to members of the ERM family of membrane-cytoskeleton adaptors. The PDZ domains within EBP50 bind to the carboxy termini of such target proteins as beta2 adrenergic receptor, platelet-derived growth factor receptor (PDGFR), and the cystic fibrosis conductance regulator (CFTR). The PDZ domains are also believed to be involved in the oligomerization of EBP 50 to form multiprotein complexes which helps to facilitate the formation of functional signalling complexes. EBP 50 has been shown to link integral membrane proteins to the cytoskeleton by binding to members of the ERM family of proteins, which bind to F-actin. Through these interactions, EBP 50 is implicated in the localization of interactive groups of proteins into subcellular domains and in the regulation of activity of those interacting proteins. Immunohistochemical studies have shown that EBP 50 is found exclusively at the apical membranes of epithelial cells.

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 9368
Alternate Names
  • sodium/hydrogen exchanger regulatory factor 1
  • Sodium-hydrogen exchanger regulatory factor 1
  • Na+/H+ exchange regulatory co-factor
  • Regulatory cofactor of Na(+)/H(+) exchanger
  • Na(+)/H(+) exchange regulatory cofactor NHE-RF1
  • Ezrin-radixin-moesin-binding phosphoprotein 50
  • ezrin-radixin-moesin binding phosphoprotein-50
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatoryfactor 1
  • NHERF1solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1
  • NHERFNPHLOP2
  • EBP50NHERF-1
  • Solute carrier family 9 isoform A3 regulatory factor 1
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1

Research Areas for NHERF-1

Find related products by research area and learn more about each of the different research areas below.

Cytoskeleton Markers
Signal Transduction

PTMs for NHERF-1

Learn more about PTMs related to NHERF-1.

Phosphorylation

Bioinformatics Tool for NHERF-1

Discover related pathways, diseases and genes to NHERF-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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