Neuroglycan C/CSPG5 Products

Description

Many cellular activities depend on the interaction of cells with the surrounding extracellular matrix (ECM). Most cells, in intact tissue and in culture, are attached to an ECM. Epithelial cells are associated with the basement membrane; fibroblastic cells are usually embedded in a pericellular mesh of fibrils, and tissue culture cells usually grow on a substrate which is covered by various ECM components. Studies have indicated that the matrix or its various isolated components provide not only adhesive surfaces for cells to grow on but also have effects on the rate of cell growth, mobility, morphogenesis and differentiation. Within the ECM several glycoproteins and proteoglycans have been identified. It has been proposed that the different constituents interact with each other in a rather complex fashion. The poor antigenicity of proteoglycans especially their glycoaminoglycan (GAG) moieties make it difficult to localize these molecules in tissue and cell culture. Monoclonal Anti-Chondroitin Sulfate can be used to study chondroitin sulfate proteoglycan (CSPG) distribution and its relationships to specific cell-substrate contacts.

Bioinformatics

Uniprot	NP_006565 Human O95196 Human
Product By Gene ID	10675
Alternate Names	CALEB chondroitin sulfate proteoglycan 5 (neuroglycan C) chondroitin sulfate proteoglycan 5 MGC44034 Neuroglycan C NGCAcidic leucine-rich EGF-like domain-containing brain protein

Research Areas for Neuroglycan C/CSPG5

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Neuroscience