NEK6 Products

Antibodies
Lysates
NEK6 Overexpression Lysate
NEK6 Overexpression Lysate
NBP2-10192
Species: Hu
Applications: WB
NEK6 Overexpression Lysate
NEK6 Overexpression Lysate
NBP2-10193
Species: Hu
Applications: WB
NEK6 Overexpression Lysate
NEK6 Overexpression Lysate
NBP2-10144
Species: Hu
Applications: WB
Proteins
Recombinant Human NEK6 GST (N ...
Recombinant Human NEK6 GST (N-Term...
H00010783-P01
Species: Hu
Applications: WB, ELISA, PA, AP, KA
Recombinant Human NEK6 GST (N ...
Recombinant Human NEK6 GST (N-Term...
H00010783-Q01
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human NEK6 Protei ...
Recombinant Human NEK6 Protein
NBP1-99495
Species: Hu
Applications: PAGE, Bioactivity

Description

NEK6 encodes a NEK type protein kinase, which contains a C-terminal NIMA-like catalytic domain. The protein is believed to regulate chromatin condensation in mammalian cells via phosphorylation of histones H1 and H3, and it has been shown to phosphorylate ribosomal S6 protein kinase (S6K1) and serum and glucocorticoid induced protein kinase (SGK1), which regulate diverse cellular processes. The protein also has been shown to bind NEK9, another NIMA-related kinase which regulates chromosome alignment and segregation. At least three mRNA transcripts have been identified, 1.6-, 2.6-, and 9.5-kb. The NEK6 gene is localized to 9q33-34, a region at which the loss of heterozygosity is associated with transitional cell carcinomas. NEK6 expression has been documented in many normal human tissues, including blood, brain, heart, liver, lung, skeletal muscle, spleen and testis. ESTs have been isolated from numerous tissue libraries, especially normal cervix and amnion and cancerous bone marrow.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 10783
Alternate Names
  • serine/threonine-protein kinase Nek6
  • EC 2.7.11.1
  • putative serine-threonine protein kinase
  • Protein kinase SID6-1512
  • NimA-related protein kinase 6
  • Never in mitosis A-related kinase 6
  • SID6-1512
  • NIMA (never in mitosis gene a)-related kinase 6

Research Areas for NEK6

Find related products by research area and learn more about each of the different research areas below.

GPCR
Protein Kinase

PTMs for NEK6

Learn more about PTMs related to NEK6.

Phosphorylation
Ubiquitination

Bioinformatics Tool for NEK6

Discover related pathways, diseases and genes to NEK6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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