NEDP1/SENP8 Products

Antibodies
Lysates
NEDP1/SENP8 Overexpression Ly ...
NEDP1/SENP8 Overexpression Lysate
NBL1-15813
Species: Hu
Applications: WB
Proteins
NEDP1/SENP8 Recombinant Prote ...
NEDP1/SENP8 Recombinant Protein An...
NBP1-85259PEP
Species: Hu
Applications: AC

Description

NEDD8 (MIM 603171) is a ubiquitin-like protein that becomes conjugated to the cullin (see CUL1; MIM 603134) subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. NEDD8-specific deneddylases, such as NEDP1, or DEN1, are required to process the NEDD8 propeptide at a C-terminal diglycine motif and to remove NEDD8 from cullins (Gan-Erdene et al., 2003 [PubMed 12759363]).[supplied by OMIM]

Bioinformatics

Entrez Human
Rat
Mouse
Uniprot Human
Human
Human
Human
Alternate Names
  • DEN1deneddylase-1
  • deneddylase 1
  • Deneddylase-1
  • EC 3.4.22.-
  • HsT17512
  • NEDD8-specific protease 1
  • NEDP1NEDD8 specific-protease cysteine 2
  • Protease, cysteine 2
  • protease, cysteine, 2 (NEDD8 specific)
  • PRSC2
  • Sentrin/SUMO-specific protease SENP8
  • sentrin-specific protease 8
  • SUMO sentrin specific protease family member 8
  • SUMO/sentrin specific peptidase family member 8
  • SUMO/sentrin specific protease family member 8