This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]. Transcript Variant: This variant (delta) represents the longer transcript and encodes the longer isoform (delta). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
![Western Blot Nectin-2/CD112 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Nectin-2_AF2229_Western_Blot_9317.jpg)
![Sandwich ELISA Nectin-2/CD112 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/Nectin-2-CD112-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79431-img0001.jpg)
![N/A Nectin-2/CD112 [Biotin]](http://images.novusbio.com/fullsize2/dy2229-05_human-nectin-2-cd112-duoset-elisa-5-plate-2522022102954.jpg)
![SEC-MALS Nectin-2/CD112 [Unconjugated]](http://images.novusbio.com/fullsize/2229-n2_recombinant-human-nectin-2-cd112-protein-sec-mals-224202616404.jpg)
![Binding Activity Nectin-2/CD112 [Unconjugated]](http://images.novusbio.com/fullsize2/10485-n2_recombinant-cynomolgus-monkey-nectin-2-cd112-fc-protein-cf-binding-activity-135202015715.jpg)
![Binding Activity Nectin-2/CD112 [Biotin]](http://images.novusbio.com/fullsize2/avi2229_recombinant-human-nectin-2-cd112-his-tag-avi-tag-protein-cf-binding-activity-2012022103035.jpg)
![Immunocytochemistry Nectin-2/CD112 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Nectin2_AF2229_Immunocytochemistry__Immunofluorescence_21146.jpg)
![Immunohistochemistry Nectin-2/CD112 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Nectin2_AF2229_Immunohistochemistry_21147.jpg)
![Simple Western Nectin-2/CD112 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Nectin2_AF2229_Simple_Western_21749.jpg)
![Western Blot Nectin-2/CD112 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af2229_human-nectin-2-cd112-affinity-purified-polyclonal-ab-4120241240231.jpg)
![SDS-PAGE Nectin-2/CD112 [Unconjugated]](http://images.novusbio.com/fullsize2/Nectin2_10485N2_3228.jpg)
![SDS-PAGE Nectin-2/CD112 [Biotin]](http://images.novusbio.com/fullsize2/avi2229_recombinant-human-nectin-2-cd112-his-tag-avi-tag-protein-cf-sds-page-2012022104416.jpg)