NCAPD3 Products

Antibodies
NCAPD3 Antibody
NCAPD3 Antibody
NB100-1573
Species: Hu, Primate, Rhesus Macaque
Applications: WB, IP
Host: Rabbit Polyclonal
NCAPD3 Antibody (1D5)
NCAPD3 Antibody (1D5)
H00023310-M01
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
Lysates
NCAPD3 Overexpression Lysate ...
NCAPD3 Overexpression Lysate (Native)
NBP2-07194
Applications: WB
RNAi
NCAPD3 RNAi
NCAPD3 RNAi
H00023310-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Smad3 is a 50 kDa member of a family of proteins that act as key mediators of TGF beta superfamily signaling in cell proliferation, differentiation and development. The Smad family is divided into three subclasses: receptor regulated Smads, activin/TGF beta receptor regulated (Smad2 and 3) or BMP receptor regulated (Smad 1, 5, and 8); the common partner, (Smad4) that functions via its interaction to the various Smads; and the inhibitory Smads, (Smad6 and 7). Activated Smad3 oligomerizes with Smad4 upon TGF beta stimulation and translocates as a complex into the nucleus, allowing its binding to DNA and transcription factors. Phosphorylation of the two TGF beta dependent serines 423 and 425 in the C terminus of Smad3 is critical for Smad3 transcriptional activity and TGF beta signaling.

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 23310
Alternate Names
  • hHCP-6
  • Non-SMC condensin II complex subunit D3
  • FLJ42888
  • CAPD3
  • CAP-D3
  • hCAP-D3condensin-2 complex subunit D3
  • KIAA0056MGC104671
  • hcp-6
  • non-SMC condensin II complex, subunit D3

Pathways for NCAPD3

View related products by pathway and learn more about each of the pathways below.

Cell Cycle
Prophase
Mitosis
Demethylation

Research Areas for NCAPD3

Find related products by research area and learn more about each of the different research areas below.

DNA Repair

PTMs for NCAPD3

Learn more about PTMs related to NCAPD3.

Demethylation

Bioinformatics Tool for NCAPD3

Discover related pathways, diseases and genes to NCAPD3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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