NCAPD3 Products

Antibodies
NCAPD3 Antibody
NCAPD3 Antibody
NB100-1573
Species: Hu
Applications: WB, ICC/IF, IP
Host: Rabbit Polyclonal
NCAPD3 Antibody (1D5) - Azide ...
NCAPD3 Antibody (1D5) - Azide and ...
H00023310-M01
Species: Hu
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
NCAPD3 Antibody - BSA Free
NCAPD3 Antibody - BSA Free
NBP3-47379
Species: Hu
Applications: WB, ELISA, IP
Host: Rabbit Polyclonal
Lysates
NCAPD3 Overexpression Lysate
NCAPD3 Overexpression Lysate
NBP2-07194
Species: Hu
Applications: WB
Proteins
NCAPD3 Recombinant Protein An ...
NCAPD3 Recombinant Protein Antigen
NBP2-55493PEP
Species: Hu
Applications: AC

Description

Smad3 is a 50 kDa member of a family of proteins that act as key mediators of TGF beta superfamily signaling in cell proliferation, differentiation and development. The Smad family is divided into three subclasses: receptor regulated Smads, activin/TGF beta receptor regulated (Smad2 and 3) or BMP receptor regulated (Smad 1, 5, and 8); the common partner, (Smad4) that functions via its interaction to the various Smads; and the inhibitory Smads, (Smad6 and 7). Activated Smad3 oligomerizes with Smad4 upon TGF beta stimulation and translocates as a complex into the nucleus, allowing its binding to DNA and transcription factors. Phosphorylation of the two TGF beta dependent serines 423 and 425 in the C terminus of Smad3 is critical for Smad3 transcriptional activity and TGF beta signaling.

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 23310
Alternate Names
  • CAPD3
  • CAP-D3
  • FLJ42888
  • hCAP-D3condensin-2 complex subunit D3
  • hcp-6
  • hHCP-6
  • KIAA0056MGC104671
  • Non-SMC condensin II complex subunit D3
  • non-SMC condensin II complex, subunit D3

Research Areas for NCAPD3

Find related products by research area and learn more about each of the different research areas below.

DNA Repair