Myogenin Products

Antibodies
Myogenin Antibody (671037)
Myogenin Antibody (671037)
MAB66861
Species: Hu
Applications: WB, ICC
Host: Mouse Monoclonal
Lysates
Myogenin Overexpression Lysat ...
Myogenin Overexpression Lysate (Na...
NBL1-13444
Applications: WB
Myogenin Overexpression Lysat ...
Myogenin Overexpression Lysate (De...
H00004656-T02
Species: Hu
Applications: WB
Proteins
Myogenin Recombinant Protein
Myogenin Recombinant Protein
H00004656-P01
Species: Hu
Applications: WB, ELISA, PA
Myogenin Recombinant Protein ...
Myogenin Recombinant Protein Antigen
NBP1-89980PEP
Species: Hu
Applications: AC
RNAi
Myogenin RNAi
Myogenin RNAi
H00004656-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
Myogenin RNAi
Myogenin RNAi
H00004656-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs. Transfection of myogenin and other family members into a variety of non-muscle cells has been shown to either convert these cells to myogenic cells, or to transcriptionally activate a set of otherwise unexpressed muscle-specific genes. In addition to activating muscle specific genes, members of the MyoD family members activate their own transcription and transactivate the transcription of other MyoD family members. For example, transfection of myogenin into 10T1/2 cells or Swiss 3T3 cells results in the activation of theendogenous myogenin gene as well as transactivation of MyoD. Likewise, the transfection of MyoD into these cells results in the activation of MyoD as well as the transactivation of myogenin. Each member of the MyoD family has distinct roles in muscle development; myogenin plays a key role in muscle maturation. Myogenin migrates at a molecular weight of approx. 34 kDa by SDS-PAGE.

Bioinformatics

Uniprot Human
Human
Human
Human
Rat
Product By Gene ID 4656
Alternate Names
  • MYOGENIN
  • Myf-4
  • Myogenic factor 4
  • BHLHC3
  • Class C basic helix-loop-helix protein 3
  • MYF4myogenin
  • bHLHc3Myogenic factor-4; myogenin
  • myf-4
  • myogenin (myogenic factor 4)

Research Areas for Myogenin

Find related products by research area and learn more about each of the different research areas below.

Cancer
Stem Cell Markers
Transcription Factors and Regulators

Bioinformatics Tool for Myogenin

Discover related pathways, diseases and genes to Myogenin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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