Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IP, Mycoplasma
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Ba
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Description
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
4595 |
| Alternate Names |
- EC 3.2.2
- EC 3.2.2.-
- EC 3.2.2.31
- hMYH
- MGC4416
- MutY homolog
- MUTYH
- Muyth
- MYH
- MYHA/G-specific adenine DNA glycosylase
|
Research Areas for MYH
Find related products by research area and learn more about each of the different research areas below.
Cancer
