MTHFD1 Products

Antibodies
MTHFD1 Antibody
MTHFD1 Antibody
NBP1-82612
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
MTHFD1 Antibody
MTHFD1 Antibody
NBP1-82610
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
MTHFD1 Antibody
MTHFD1 Antibody
NBP1-82611
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
MTHFD1 Antibody Pair
MTHFD1 Antibody Pair
H00004522-PW1
Species: Hu
Applications: WB, IP
Lysates
MTHFD1 Overexpression Lysate ...
MTHFD1 Overexpression Lysate (Dena...
H00004522-T01
Species: Hu
Applications: WB
MTHFD1 Overexpression Lysate ...
MTHFD1 Overexpression Lysate (Native)
NBP2-07686
Applications: WB
Proteins
MTHFD1 Recombinant Protein
MTHFD1 Recombinant Protein
H00004522-P01
Species: Hu
Applications: WB, ELISA, PA
MTHFD1 Recombinant Protein An ...
MTHFD1 Recombinant Protein Antigen
NBP1-82611PEP
Species: Hu
Applications: AC
MTHFD1 Recombinant Protein An ...
MTHFD1 Recombinant Protein Antigen
NBP1-82612PEP
Species: Hu
Applications: AC

Description

MTHFD1 encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. [provided by RefSeq]

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 4522
Alternate Names
  • EC 6.3.4.3
  • C1-THF synthase
  • MTHFDcytoplasmic C-1-tetrahydrofolate synthase
  • MTHFCC-1-tetrahydrofolate synthase, cytoplasmic
  • methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methylenetetrahydrofolatecyclohydrolase, 10-formyltetrahydrofolate synthetase
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1

Research Areas for MTHFD1

Find related products by research area and learn more about each of the different research areas below.

Stem Cell Markers

PTMs for MTHFD1

Learn more about PTMs related to MTHFD1.

Methylation
Reduction

Bioinformatics Tool for MTHFD1

Discover related pathways, diseases and genes to MTHFD1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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