MRPS11 Products

Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Sequence analysis identified two transcript variants that encode different protein isoforms. Transcript Variant: This variant (1) is the predominant variant and it encodes isoform a.

Bioinformatics

Product By Gene ID	64963
Alternate Names	28S ribosomal protein S11, mitochondrial Cervical cancer proto-oncogene 2 protein FLJ22512 FLJ23406 HCC-2S11mt mitochondrial ribosomal protein S11 MRP-S11 RPMS11