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MRPL43, also known as Mitochondrial Ribosomal Protein L43, contains several isoforms that are 23 kDa, 22 kDa, 18 kDa, and 17 kDa, and has been associated with protein synthesis in the mitochondria, though its specific function is still unknown. Current research is being conducted on MRPL43 and its connection to several diseases and disorders, including chronic progressive external ophthalmoplegia, prostatitis, Alzheimer's disease, and paraplegia. The protein interacts with ICT1, ARRB2, EIF1B, DDX56, and AARS2.
