Mrc2 Products

Antibodies
Mrc2 Antibody
Mrc2 Antibody
AF5770
Species: Hu
Applications: WB, IHC
Host: Goat Polyclonal
Mrc2 Antibody
Mrc2 Antibody
AF4789
Species: Mu
Applications: WB
Host: Sheep Polyclonal
Mrc2 Antibody
Mrc2 Antibody
NBP1-85768
Species: Hu, Rt
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Mrc2 Overexpression Lysate (N ...
Mrc2 Overexpression Lysate (Native)
NBP2-07680
Applications: WB
Proteins
Recombinant Human Mrc2 Protei ...
Recombinant Human Mrc2 Protein
H00009902-Q01
Species: Hu
Applications: WB, ELISA, PA
Mrc2 Recombinant Protein Anti ...
Mrc2 Recombinant Protein Antigen
NBP1-85768PEP
Species: Hu
Applications: AC
RNAi
Mrc2 RNAi
Mrc2 RNAi
H00009902-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

MRC2, also known as C-type mannose receptor 2, is a 1,479 amino acid protein that is 167 kDa, plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands, may be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface, and may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. Disease research is currently being studied with relations to MRC2 and breast cancer, aortic aneurysm, prostate cancer, progression of osteoarthritis, prostatitis,s, schizophrenia, tuberculosis, immunodeficiency, and hepatitis. Interactions with this protein have shown to involve NDEL1, IL10, TGFB1, TGFB2, TGFB3, and UBC in antigen processing-cross presentation, cross-presentation of soluble exogenous antigens (endosomes), adaptive immune system, class I MHC mediated antigen processing & presentation, immune system, phagosome, and tuberculosis pathways.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 9902
Alternate Names
  • Urokinase receptor-associated protein
  • CD280 antigen
  • Macrophage mannose receptor 2
  • urokinase plasminogen activator receptor-associated protein
  • Endocytic receptor 180
  • UPARAPendocytic receptor (macrophage mannose receptor family)
  • CD280C-type mannose receptor 2
  • KIAA0709FLJ35911
  • CLEC13EUPAR-associated protein
  • ENDO180C-type lectin domain family 13 member E
  • Urokinase-type plasminogen activator receptor-associated protein
  • mannose receptor, C type 2

PTMs for Mrc2

Learn more about PTMs related to Mrc2.

Cleavage
Glycosylation
Phosphorylation

Bioinformatics Tool for Mrc2

Discover related pathways, diseases and genes to Mrc2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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