MMP-17 Products

Antibodies
MMP-17 Antibody (823511)
MMP-17 Antibody (823511)
MAB7796
Species: Hu
Applications: Neut
Host: Mouse Monoclonal
MMP-17 Antibody
MMP-17 Antibody
22680002
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
MMP-17 Antibody (MM0638-12N24 ...
MMP-17 Antibody (MM0638-12N24)
NBP2-32725
Species: Hu
Applications: B/N, ELISA
Host: Mouse Monoclonal
Proteins
Recombinant Human MMP-17 Prot ...
Recombinant Human MMP-17 Protein
P4928
Species: Hu
Applications: Func, PAGE
RNAi
MMP-17 RNAi
MMP-17 RNAi
H00004326-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Membrane type (MT) matrix metalloproteinases (MMPs) are recently recognized members of the family of Zn(2+)- and Ca(2+)-dependent MMPs. MMP-17 is, therefore, a competent Zn(2+)-dependent MMP with unique specificity among synthetic substrates and the capability to both degrade gelatin and activate progelatinase A (1). (MMP-17) is expressed mainly in the brain, leukocytes, the colon, the ovary, and the testis. The expression of MMP-17 in leukocytes together with its putative membrane localization suggest that this enzyme could be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators such as tumor necrosis factor-alpha (2). glycosylphospha-tidylinositol (GPI) anchoring of MT4-MMP on the cell surface indicates a unique biological function and character for this proteinase (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 4326
Alternate Names
  • membrane-type matrix metalloproteinase 4
  • membrane-type-4 matrix metalloproteinase
  • MT4-MMP
  • MT-MMP 4
  • MMP-17
  • matrix metalloproteinase-17
  • MTMMP4
  • MT4MMP
  • matrix metalloproteinase 17 (membrane-inserted)
  • matrix metallopeptidase 17 (membrane-inserted)

Pathways for MMP-17

View related products by pathway and learn more about each of the pathways below.

Localization
Transport
Cell Migration
Translation
Eosinophil Migration
Tissue Remodeling
Proteolysis
Angiogenesis
Ovulation
Oxidative Phosphorylation

PTMs for MMP-17

Learn more about PTMs related to MMP-17.

Cleavage
Biotinylation
Glycosylation
Gpi Anchoring
Deglycosylation

Bioinformatics Tool for MMP-17

Discover related pathways, diseases and genes to MMP-17. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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