Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Monoclonal
Host: Mouse Monoclonal
Applications: Enzyme Activity
Membrane type (MT) matrix metalloproteinases (MMPs) are recently recognized members of the family of Zn(2+)- and Ca(2+)-dependent MMPs. MMP-17 is, therefore, a competent Zn(2+)-dependent MMP with unique specificity among synthetic substrates and the capability to both degrade gelatin and activate progelatinase A (1). (MMP-17) is expressed mainly in the brain, leukocytes, the colon, the ovary, and the testis. The expression of MMP-17 in leukocytes together with its putative membrane localization suggest that this enzyme could be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators such as tumor necrosis factor-alpha (2). glycosylphospha-tidylinositol (GPI) anchoring of MT4-MMP on the cell surface indicates a unique biological function and character for this proteinase (3).
|Product By Gene ID
- membrane-type matrix metalloproteinase 4
- membrane-type-4 matrix metalloproteinase
- MT-MMP 4
- matrix metalloproteinase-17
- matrix metalloproteinase 17 (membrane-inserted)
- matrix metallopeptidase 17 (membrane-inserted)
Bioinformatics Tool for MMP-17
Discover related pathways, diseases and genes to MMP-17. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.