MKLP1 Products

Antibodies
MKLP1 Antibody
MKLP1 Antibody
NB100-211
Species: Hu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Conjugate Catalog # Availability Size Price
MKLP1 Antibody
MKLP1 Antibody
NBP1-58126
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
MKLP1 Antibody
MKLP1 Antibody
H00009493-B01P
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Polyclonal
Lysates
MKLP1 Overexpression Lysate ( ...
MKLP1 Overexpression Lysate (Denat...
H00009493-T01
Species: Hu
Applications: WB

Description

Using the CHO1 monoclonal antibody, Sellitto and Kuriyama (1988) identified a spindle antigen that was shown by Nislow et al. (1990) to be required for mitotic progression. By using the CHO1 antibody to screen a HeLa cell cDNA library, Nislow et al. (1992) isolated a KNSL5 cDNA, which they called MKLP1 (mitotic kinesin-like protein-1), that encodes this antigen. The N-terminal region of the deduced 961-amino acid protein contains a 350-residue domain that shares 30 to 45% identity with the motor domains of other members of the kinesin superfamily. The C-terminal region shows little identity with other kinesins. A central region contains heptad repeats of hydrophobic residues that may assemble into a coiled-coil structure similar to kinesin and myosin heavy chain proteins. The protein also contains a putative nuclear localization signal and 2 consensus phosphorylation sites characteristic of nuclear proteins.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 9493
Alternate Names
  • mitotic kinesin-like 1
  • kinesin-like 5 (mitotic kinesin-like protein 1)
  • kinesin-like protein KIF23
  • MKLP-1
  • KNSL5CHO1
  • MKLP1Mitotic kinesin-like protein 1
  • Kinesin-like protein 5
  • kinesin family member 23

Research Areas for MKLP1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Core ESC-Like Genes
DNA Repair
Stem Cell Markers

PTMs for MKLP1

Learn more about PTMs related to MKLP1.

Phosphorylation
Cleavage
Glycosylation
Acetylation
Dephosphorylation

Bioinformatics Tool for MKLP1

Discover related pathways, diseases and genes to MKLP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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