mGluR4 Products

Antibodies
mGluR4 Antibody
mGluR4 Antibody
AF7387
Species: Hu
Applications: Flow, IHC
Host: Sheep Polyclonal
mGluR4 Antibody
mGluR4 Antibody
NBP1-67577
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
mGluR4 Antibody
mGluR4 Antibody
NLS4713
Species: Hu, Mu, Po, Mk, Pm, Rb, Canine, Hamster, Rat
Applications: WB, IHC-P
Host: Rabbit Polyclonal
Lysates
mGluR4 Overexpression Lysate ...
mGluR4 Overexpression Lysate (Native)
NBL1-11349
Applications: WB
Proteins
mGluR4 Recombinant Protein
mGluR4 Recombinant Protein
H00002914-G01-10ug
Species: Hu
RNAi
mGluR4 RNAi
mGluR4 RNAi
H00002914-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group III includes GRM4, GRM6, GRM7, and GRM8 receptors that are linked to the inhibition of the cyclic AMP signaling cascade. Two protein isoforms have been reported in rat (mGluR4a 912 aa; mGluRb 983 aa), which differ at the C-terminus. GRM4 has been reported in various regions of the brain, eye, and spinal cord. ESTs have been isolated from brain, embryo, melanocyte/uterus/fetal heart, nerve, and testis libraries. Caution: GLUR4 refers to Ionotropic Glutamate Receptor 4, not to Metabotropic Glutamate Receptor 4 (mGLUR4).

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 2914
Alternate Names
  • mGluR4
  • mGlu4
  • GPRC1Dmetabotropic glutamate receptor 4
  • MGLUR4glutamate metabotropic receptor 4
  • MGC177594
  • glutamate receptor, metabotropic 4

Pathways for mGluR4

View related products by pathway and learn more about each of the pathways below.

Translation
Circadian Rhythm
Synaptic Transmission
Taste Perception

Research Areas for mGluR4

Find related products by research area and learn more about each of the different research areas below.

GPCR
Metabotropic Glutamate Receptors
Neuronal Cell Markers
Neuroscience
Neurotransmission
Vision

PTMs for mGluR4

Learn more about PTMs related to mGluR4.

Phosphorylation

Bioinformatics Tool for mGluR4

Discover related pathways, diseases and genes to mGluR4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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