Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Rt
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: Enzyme Activity
Species: Hu
Applications: AC
Description
MGAT4A encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
11320 |
Alternate Names |
- alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
- alpha-1,3-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
- EC 2.4.1.145
- GlcNAc-T IVa
- GNT-IV
- GnT-IVa
- GnT-Iva
- GNT-IVA
- isoenzyme A
- isozyme A
- mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
- mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
- N-acetylglucosaminyltransferase IVa
- N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa
- UDP-GlcNAc:a-1,3-D-mannoside b-1,4-acetylglucosaminyltransferase IV
- UDP-N-acetylglucosamine: alpha-1,3-D-mannosidebeta-1,4-N-acetylglucosaminyltransferase IVa
- UDP-N-acetylglucosamine:alpha1,3-d-mannosidebeta1,4-N-acetylglucosaminyltransferase
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Research Areas for MGAT4A
Find related products by research area and learn more about each of the different research areas below.
Golgi Apparatus Markers