MGAT2 Products

Description

The product of the MGAT2 gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complexN-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, ahydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead tocarbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcriptvariants with a spliced 5' UTR may exist, but their biological validity has not been determined. (provided byRefSeq)

Bioinformatics

Entrez	4247 Human
Uniprot	AAH06390 Human GNT2_HUMAN Human NP_002399 Human Q10469 Human
Product By Gene ID	4247
Alternate Names	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Beta-1,2-N-acetylglucosaminyltransferase II CDG2A EC 2.4.1.143 GlcNAc-T II GLCNACTII GNT2 GNT-IICDGS2 Mannoside acetylglucosaminyltransferase 2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II UDP-N-acetylglucosamine:alpha-6-D-mannosidebeta-1,2-N-acetylglucosaminyltransferase II