Meprin alpha Subunit/MEP1A Products

Description

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded alpha and/or beta subunits. Homooligomers of meprin-alpha are secreted; oligomers containing meprin-beta are associated with the plasma membrane. Substrates include bioactive peptides and extracellular matrix proteins.

Bioinformatics

Entrez	4224 Human
Uniprot	Q16819 Human
Product By Gene ID	4224
Alternate Names	bA268F1.1 (meprin A alpha (PABA peptide hydrolase)) EC 3.4.24 EC 3.4.24.18 Endopeptidase-2 endopeptidase-2 meprin A subunit alpha meprin A, alpha (PABA peptide hydrolase) N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha PABA peptide hydrolase PPH alpha PPHA