Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, KD
Host: Rabbit Polyclonal
Species: Hu, Mu, Bv
Applications: WB, IHC, IP (-)
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
MCM6 is encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Bioinformatics
| Entrez |
Mouse
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
4175 |
| Alternate Names |
- DNA replication licensing factor MCM6
- EC 3.6.4.12
- MCG40308
- MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S.cerevisiae)
- MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe)
- minichromosome maintenance complex component 6
- minichromosome maintenance deficient (mis5, S. pombe) 6
- minichromosome maintenance deficient 6 homolog (S. cerevisiae)
- minichromosome maintenance deficient 6 homolog
- MIS5 homolog
- Mis5
- P105MCM
- p105MCM
|
