MCM4 Products

Antibodies
MCM4 Antibody
MCM4 Antibody
H00004173-B01P
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Polyclonal
MCM4 Antibody
MCM4 Antibody
NBP1-33105
Species: Hu, Mu
Applications: WB, ChIP, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
MCM4 Antibody
MCM4 Antibody
NB100-290
Species: Hu, Mu, Xp, Bovine, Equine, Guinea Pig, Primate, Rabbit, Bat
Applications: WB, PLA, IP (-)
Host: Rabbit Polyclonal
Antibody Pairs
MCM4 Antibody Pair
MCM4 Antibody Pair
H00004173-AP21
Species: Hu
Applications: S-ELISA
MCM4 Antibody Pair
MCM4 Antibody Pair
H00004173-AP22
Species: Hu
Applications: S-ELISA
MCM4 Antibody Pair
MCM4 Antibody Pair
H00004173-PW1
Species: Hu
Applications: WB, IP
Lysates
MCM4 Overexpression Lysate (D ...
MCM4 Overexpression Lysate (Denatu...
H00004173-T01
Species: Hu
Applications: WB
MCM4 Overexpression Lysate (N ...
MCM4 Overexpression Lysate (Native)
NBP2-04808
Applications: WB
MCM4 Overexpression Lysate (N ...
MCM4 Overexpression Lysate (Native)
NBL1-12953
Applications: WB
Proteins
MCM4 Recombinant Protein
MCM4 Recombinant Protein
H00004173-P01
Species: Hu
Applications: WB, ELISA, PA
MCM4 Partial Recombinant Prot ...
MCM4 Partial Recombinant Protein
H00004173-Q01
Species: Hu
Applications: WB, ELISA, PA
MCM4 Recombinant Protein Anti ...
MCM4 Recombinant Protein Antigen
NBP1-85728PEP
Species: Hu
Applications: AC
RNAi
MCM4 RNAi
MCM4 RNAi
H00004173-R03
Species: Hu
MCM4 RNAi
MCM4 RNAi
H00004173-R04
Species: Hu

Description

MCM4 is encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 4173
Alternate Names
  • EC 3.6.4.12
  • CDC21 homolog
  • minichromosome maintenance deficient 4
  • P1-CDC21
  • MCM4 minichromosome maintenance deficient 4
  • CDC21
  • homolog of S. pombe cell devision cycle 21
  • hCdc21
  • DNA replication licensing factor MCM4
  • MGC33310
  • MCM4 minichromosome maintenance deficient 4 (S. cerevisiae)
  • CDC54
  • P1-Cdc21
  • minichromosome maintenance complex component 4

Research Areas for MCM4

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Core ESC-Like Genes
DNA Double Strand Break Repair
DNA Repair
Stem Cell Markers

PTMs for MCM4

Learn more about PTMs related to MCM4.

Phosphorylation
Cleavage
Dephosphorylation
Ubiquitination
Hydroxylation
Acetylation

Bioinformatics Tool for MCM4

Discover related pathways, diseases and genes to MCM4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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