MBD2 Products

Antibodies
MBD2 Antibody
MBD2 Antibody
NB100-81656
Species: Hu, Mu, Guinea Pig, Primate, Porcine, Rabbit, Squirrel
Applications: ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
MBD2 Antibody
MBD2 Antibody
NB100-55415
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
MBD2 Antibody
MBD2 Antibody
NB100-81657
Species: Hu, Mu, Canine, Guinea Pig, Primate, Porcine
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Kits
MBD2 Assay Kit
MBD2 Assay Kit
KA0675
Applications: Func
RNAi
MBD2 RNAi
MBD2 RNAi
H00008932-R02
Species: Hu
MBD2 RNAi
MBD2 RNAi
H00008932-R01
Species: Hu

Description

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. [provided by RefSeq]

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 8932
Alternate Names
  • Demethylase
  • DKFZp586O0821
  • methyl-CpG-binding domain protein 2
  • DMTase
  • demethylase
  • Methyl-CpG-binding protein MBD2
  • NY-CO-41
  • methyl-CpG binding domain protein 2

Research Areas for MBD2

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Chromatin Research
Stem Cell Markers

Bioinformatics Tool for MBD2

Discover related pathways, diseases and genes to MBD2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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