Species: Hu, Mu, Rt, Po, Bv
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Ce
Applications: WB, ELISA, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq]
Bioinformatics
| Entrez |
Human |
| Uniprot |
Human |
| Product By Gene ID |
4143 |
| Alternate Names |
- AdoMet synthase 1
- adoMet synthetase 1
- AMS1
- MAT
- MATA1MAT 1
- MAT-I/III
- Methionine adenosyltransferase 1
- methionine adenosyltransferase I, alpha
- Methionine adenosyltransferase I/III
- S-adenosylmethionine synthase isoform type-1
- S-adenosylmethionine synthetase isoform type-1
- SAMS
- SAMS1EC 2.5.1.6
|
Research Areas for MAT1A
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism