MAT1/2A Products


MAT1A and MAT2A are catalytic subunits of methionine adenosyltransferase (MAT), which catalyzes the formation of S-adenosyltransferase for methionine catabolism. Inactivation of MAT1A has been linked to liver disease. In addition, in certain liver cancers, expression of MAT1A is replaced by expression of MAT1B. Overexpression of MAT2A has also been observed in colon cancer, leading to the proposal that MAT2A facilitates cancer cell growth.

MAT1A and MAT2A antibodies are useful tools for cancer research and liver function research.


Entrez Human
Uniprot Human
Product By Gene ID 4144
Alternate Names
  • MAT 2
  • Methionine adenosyltransferase II
  • MAT-II
  • AMS2
  • Methionine adenosyltransferase 2
  • S-adenosylmethionine synthetase isoform type-2
  • AdoMet synthase 2
  • S-adenosylmethionine synthase isoform type-2
  • MATA2SAMS2adoMet synthetase 2
  • EC
  • methionine adenosyltransferase II, alpha

Research Areas for MAT1/2A

Find related products by research area and learn more about each of the different research areas below.

Amino Acids, Drugs and other small molecules
Lipid and Metabolism
Signal Transduction

Bioinformatics Tool for MAT1/2A

Discover related pathways, diseases and genes to MAT1/2A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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