MAN2B1 Products

MAN2B1 Antibody
MAN2B1 Antibody
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
MAN2B1 Antibody
MAN2B1 Antibody
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
MAN2B1 Antibody
MAN2B1 Antibody
Species: Hu
Applications: WB
Host: Mouse Polyclonal
Recombinant Human MAN2B1 Prot ...
Recombinant Human MAN2B1 Protein, CF
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  


MAN2B1 encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First, a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). Next, the 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. [provided by RefSeq]


Entrez Human
Uniprot Human
Product By Gene ID 4125
Alternate Names
  • EC 3.2.1
  • EC
  • Mannosidase alpha class 2B member 1
  • Mannosidase alpha-B
  • Laman
  • Lysosomal acid alpha-mannosidase
  • alpha B, lysosomal
  • mannosidase, alpha, class 2B, member 1

Pathways for MAN2B1

View related products by pathway and learn more about each of the pathways below.

Protein Processing

Bioinformatics Tool for MAN2B1

Discover related pathways, diseases and genes to MAN2B1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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