MAGEB2 Products

Description

MAGEB2 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq]

Bioinformatics

Entrez	4113 Human
Uniprot	O15479 Human NM_002364 Human NP_002355 Human
Product By Gene ID	4113
Alternate Names	melanoma-associated antigen B2 Cancer/testis antigen 3.2 DSS/AHC critical interval MAGE superfamily 6 MGC26438 cancer/testis antigen family 3, member 2 MAGE-XP-2 CT3.2MAGE-B2 antigen DAM6MAGE XP-2 antigen DSS-AHC critical interval MAGE superfamily 6 melanoma antigen family B, 2

Diseases related to MAGEB2

Discover more about diseases related to MAGEB2.

Neoplasms
Malignant Neoplasms
Melanoma
Carcinoma
Neoplasm Metastasis
Malignant Paraganglionic Neoplasm
Mammary Neoplasms
Stomach Neoplasms
Malignant Squamous Cell Neoplasm
Lung Neoplasms
Malignant Neoplasm Of Lung
Malignant Neoplasm Of Stomach
Malignant Neoplasm Of Breast
Sarcoma
Liver Carcinoma
Head And Neck Neoplasms
Liver Neoplasms
Kidney Neoplasm
Esophageal Neoplasms
Metastatic Melanoma

Pathways for MAGEB2

View related products by pathway and learn more about each of the pathways below.

Demethylation
Reverse Transcription
Immune Response
Methylation
Cell Differentiation
Pathogenesis
Enucleation
Cytolysis
Dna Methylation
Hypersensitivity
Plasma Cell Differentiation
Spermatogenesis
Histone Acetylation

PTMs for MAGEB2

Learn more about PTMs related to MAGEB2.

Demethylation
Methylation
Acetylation

Bioinformatics Tool for MAGEB2

Discover related pathways, diseases and genes to MAGEB2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.