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GAA encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
![Western Blot LYAG/GAA Antibody (2489C) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/Lysosomal_alphaGlucosidase_MAB8329_Western_Blot_23905.jpg)
![Western Blot LYAG/GAA Antibody (2489B) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/Lysosomal_alphaGlucosidase_MAB83291_Western_Blot_24202.jpg)
![Enzyme Activity LYAG/GAA [Unconjugated]](http://images.novusbio.com/fullsize/8329-gh_recombinant-human-lysosomal-alpha-glucosidase-gaa-cf-enzyme-activity-622023983.jpg)
![Enzyme Activity LYAG/GAA [Unconjugated]](http://images.novusbio.com/fullsize/11400-gh_recombinant-mouse-lysosomal-alpha-glucosidase-gaa-cf-enzyme-activity-7920239280..jpg)
![Immunohistochemistry LYAG/GAA Antibody (2489C) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/Lysosomal_alphaGlucosidase_MAB8329_Immunohistochemistry_23608.jpg)
![Immunohistochemistry LYAG/GAA Antibody (2489B) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/Lysosomal_alphaGlucosidase_MAB83291_Immunohistochemistry_24039.jpg)
![Enzyme Activity LYAG/GAA [Unconjugated]](http://images.novusbio.com/fullsize/8329-gh_recombinant-human-lysosomal-alpha-glucosidase-gaa-cf-enzyme-activity-6220239264.jpg)
![SDS-Page LYAG/GAA [Unconjugated]](http://images.novusbio.com/fullsize/8329-gh_recombinant-human-lysosomal-alpha-glucosidase-gaa-cf-sds-page-62202393418.jpg)
![SDS-Page LYAG/GAA [Unconjugated]](http://images.novusbio.com/fullsize/11400-gh_recombinant-mouse-lysosomal-alpha-glucosidase-gaa-cf-sds-page-79202393758.jpg)