Lubricin/PRG4 Products

Description

Lubricin is a glycoprotein encoded by the PRG4 gene. It has been identified as a component of joint lubrication and synovial homeostasis by reducing friction in joints and preventing synovial cell overgrowth. It is a large, water soluble molecule that acts as a carrier for insoluble surface-active phospholipid (SAPL). Depletion of lubricin function has been associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), an arthritic-like autosomal recessive disorder.

Bioinformatics

Entrez	10216 Human 96875 Mouse
Uniprot	NP_005798 Human NP_005798.2 Human Q92954 Human
Product By Gene ID	10216
Alternate Names	bG174L6.2 (MSF: megakaryocyte stimulating factor ) bG174L6.2 CACP FLJ32635 JCAP lubricin Lubricin megakaryocyte stimulating factor Megakaryocyte-stimulating factor MSFproteoglycan 4, (megakaryocyte stimulating factor, articular superficial zoneprotein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome) proteoglycan 4 Superficial zone proteoglycan SZPHAPOarticular superficial zone protein