LKB1/STK11 Products

Antibodies
LKB1/STK11 Antibody
LKB1/STK11 Antibody
NBP2-14835
Species: Hu, Mu, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
LKB1/STK11 Antibody
LKB1/STK11 Antibody
NBP2-14834
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
LKB1/STK11 Antibody (0A3)
LKB1/STK11 Antibody (0A3)
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
Lysates
LKB1/STK11 Overexpression Lys ...
LKB1/STK11 Overexpression Lysate (...
H00006794-T01
Species: Hu
Applications: WB
LKB1/STK11 Overexpression Lys ...
LKB1/STK11 Overexpression Lysate (...
NBL1-16540
Applications: WB
Proteins
LKB1/STK11 Recombinant Protei ...
LKB1/STK11 Recombinant Protein
H00006794-P01
Species: Hu
Applications: WB, ELISA, PA
LKB1/STK11 Partial Recombinan ...
LKB1/STK11 Partial Recombinant Pro...
H00006794-Q01
Species: Hu
Applications: WB, ELISA, PA
LKB1/STK11 Recombinant Protei ...
LKB1/STK11 Recombinant Protein Ant...
NBP1-87817PEP
Species: Hu
Applications: AC
RNAi
LKB1/STK11 RNAi
LKB1/STK11 RNAi
H00006794-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Peutz-Jeghers syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. LKB1 (also designated STK11 and PJS) has been identified as the gene mutated in PJS. LKB1 is a 433 amino acid Serine/Threonine kinase with strong homology to the Xenopus cytoplasmic protein kinase XEEK1 and weaker similarity to many other protein kinases. LKB1 is ubiquitously expressed and many frameshift, deletion and splicing mutations have been identified in PJS patients. Despite the increased risk of cancer for PJS patients, LKB1 does not appear to play a major role in colorectal, testicular or breast cancers.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 6794
Alternate Names
  • PJS
  • STK11
  • Serine/threonine-protein kinase LKB1
  • serine/threonine-protein kinase 11
  • Renal carcinoma antigen NY-REN-19
  • PJS polarization-related protein LKB1
  • LKB1 serine/threonine kinase 11 (Peutz-Jeghers syndrome)
  • EC 2.7.11.1
  • serine/threonine kinase 11

Research Areas for LKB1/STK11

Find related products by research area and learn more about each of the different research areas below.

mTOR Pathway
p53 Pathway
Phospho-Specific
Protein Kinase

Bioinformatics Tool for LKB1/STK11

Discover related pathways, diseases and genes to LKB1/STK11. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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