LIS1 Products

Antibodies
LIS1 Antibody
LIS1 Antibody
NBP1-87769
Species: Hu, Mouse
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
LIS1 Antibody
LIS1 Antibody
NBP1-76815
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
LIS1 Antibody
LIS1 Antibody
NBP1-03125
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Kits
LIS1 Assay Kit
LIS1 Assay Kit
KA1354
Species: Hu
Applications: Func
LIS1 Assay/Inhibitor Screenin ...
LIS1 Assay/Inhibitor Screening Ass...
KA1355
Applications: Func
Lysates
LIS1 Overexpression Lysate (N ...
LIS1 Overexpression Lysate (Native)
NBP2-10671
Applications: WB
Proteins
LIS1 Partial Recombinant Prot ...
LIS1 Partial Recombinant Protein
H00005048-Q01
Species: Hu
Applications: WB, ELISA, PA
LIS1 Recombinant Protein
LIS1 Recombinant Protein
H00005048-P01
Species: Hu
Applications: WB, ELISA, PA
LIS1 Recombinant Protein Anti ...
LIS1 Recombinant Protein Antigen
NBP1-87769PEP
Species: Hu
Applications: AC
RNAi
LIS1 RNAi
LIS1 RNAi
H00005048-R01
Species: Hu

Description

Lissencephaly (LIS), literally meaning smooth brain, has multiple causes. Agyria, i.e., brain without convolutions or gyri, was considered a rare malformation until recent progress in neuroradiology. With this technical advantage, a number of lissencephaly syndromes have been distinguished. Classic lissencephaly (type I) is a brain malformation caused by abnormal neuronal migration at 9 to 13 weeks' gestation, resulting in a spectrum of agyria, mixed agyria / pachygyria, and pachygyria. It is characterized by an abnormally thick and poorly organized cortex with 4 primitive layers, diffuse neuronal heterotopia, enlarged and dysmorphic ventricles, and often hypoplasia of the corpus callosum. Lissencephaly is found in association with facial abnormalities in Miller-Dieker syndrome and without other major anomalies in X-linked lissencephaly and isolated lissencephaly sequence (ILS). Subcortical band heterotopia (SBH) are bilateral and symmetric ribbons of gray matter found in the central white matter between the cortex and the ventricular surface and comprise the less severe end of the lissencephaly spectrum of malformations.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 5048
Alternate Names
  • PAF acetylhydrolase 45 kDa subunit
  • PAFAHA
  • MDS
  • platelet-activating factor acetylhydrolase IB subunit alpha
  • MDCR
  • lissencephaly 1 protein
  • LIS-1
  • LIS2
  • Lissencephaly-1 protein
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa
  • platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)
  • Miller-Dieker syndrome chromosome region
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD)
  • PAFAH alpha
  • PAFAH
  • LIS1PAF-AH alpha
  • PAF-AH 45 kDa subunit
  • platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)

Research Areas for LIS1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

PTMs for LIS1

Learn more about PTMs related to LIS1.

Phosphorylation
Cleavage
Deacetylation
Myristoylation
Acetylation
Palmitoylation

Bioinformatics Tool for LIS1

Discover related pathways, diseases and genes to LIS1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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