Applications: WB, IHC
Host: Mouse monoclonal
Species: Hu, Mu(-)
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
LIME (Lck-interacting molecule) is a new raft-associated adaptor protein involved in regulation of T cell activation by coreceptors. LIME becomes tyrosine phosphorylated after cross-linking of the CD4 or CD8 coreceptors. Phospho-LIME associates with the Src family kinase Lck and its negative regulator, Csk. Ectopic expression of LIME in Jurkat T cells results in an increase of Csk in lipid rafts, increased phosphorylation of Lck and higher Ca2+ response to CD3 stimulation.
|Product By Gene ID
- Lck-interacting membrane protein
- lck-interacting transmembrane adapter 1
- Lck-interacting molecule
- Lck interacting transmembrane adaptor 1
Research Areas for LIME
Find related products by research area and learn more about each of the different research areas below.Signal Transduction
Bioinformatics Tool for LIME
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