Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Lecithin-Cholesterol Acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP) it is also responsible for a significant proportion of VLDL and LDL cholesteryl esters. LCAT, through the esterification of cholesterol, plays a role in the reverse cholesterol transport pathway by facilitating the net movement of cholesterol from peripheral tissues back to the liver for excretion. LCAT deficiency results in low levels of plasma HDL, whereas a transgenic overexpression of LCAT results in increased plasma HDL concentrations.
LCAT antibodies are useful tools for lipid and cholesterol metabolism research.
|Product By Gene ID
- phosphatidylcholine-sterol acyltransferase
- EC 184.108.40.206
- lecithin-cholesterol acyltransferasePhospholipid-cholesterol acyltransferase
Bioinformatics Tool for LCAT
Discover related pathways, diseases and genes to LCAT. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.