Species: Hu, Mu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
Lecithin-Cholesterol Acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP) it is also responsible for a significant proportion of VLDL and LDL cholesteryl esters. LCAT, through the esterification of cholesterol, plays a role in the reverse cholesterol transport pathway by facilitating the net movement of cholesterol from peripheral tissues back to the liver for excretion. LCAT deficiency results in low levels of plasma HDL, whereas a transgenic overexpression of LCAT results in increased plasma HDL concentrations.
LCAT antibodies are useful tools for lipid and cholesterol metabolism research.
Bioinformatics
Entrez |
Human Mouse |
Uniprot |
Human Human Human Human |
Product By Gene ID |
3931 |
Alternate Names |
- phosphatidylcholine-sterol acyltransferase
- EC 2.3.1.43
- lecithin-cholesterol acyltransferasePhospholipid-cholesterol acyltransferase
|
Bioinformatics Tool for LCAT
Discover related pathways, diseases and genes to LCAT. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.