Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Av, Eq, Ma-Op, Pm, Rb
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Po, Bt, Bv, Ca, Eq, Pm, Rb, Ma-Op, Pm
Applications: IHC
Host: Rabbit Polyclonal
Description
Latrophilin-2 is an Orphan-B Receptor that binds alpha-latrotoxin, a potent presynaptic neurotoxin present in the venom of the black widow spider, in a Ca2+-independent manner. As with the other two latrophilins, it shares homology with lectin, olfactomedin, and transmembrane domains, and possesses variable C-termini and various alternative-splice sites. Latrophilin-2 is endoproteolytically cleaved at the end of the GPS domain, and the two subunits remain non-covantely linked as a heterodimer. Latrophilin-2 has been reported to be expressed in brain, breast, placenta, kidney, spleen, ovary, heart, and lung. ESTs have been isolated from a wide variety of tissue libraries.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
23266 |
| Alternate Names |
- Calcium-independent alpha-latrotoxin receptor 2
- CIRL2
- CIRL-2
- CL2
- KIAA0786
- latrophilin 2
- Latrophilin homolog 1
- latrophilin homolog 2 (cow)
- latrophilin-2
- LEC1LPHH1latrophilin 1
- Lectomedin-1
- lectomedin-1
|
Research Areas for Latrophilin 2/LPHN2
Find related products by research area and learn more about each of the different research areas below.
CancerGPCR
![Western Blot Latrophilin 2/LPHN2 Antibody (1030202) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab105881_human-latrophilin-2-lphn2-mab-clone-1030202-western-blot-2912202095825.jpg)
![Intracellular Staining by Flow Cytometry Latrophilin 2/LPHN2 Antibody (1030202) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab105881_human-latrophilin-2-lphn2-mab-clone-1030202-intracellular-staining-by-flow-cytometry-6102020124531.jpg)
