Latrophilin 1/LPHN1 Products

Description

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. [provided by RefSeq]

Bioinformatics

Entrez	22859 Human
Uniprot	AAH19928 Human
Product By Gene ID	22859
Alternate Names	Calcium-independent alpha-latrotoxin receptor 1 CIRL1 CIRL-1 KIAA0821 Latrophilin 1 latrophilin-1 LEC2 LEC2CL1 Lectomedin-2 LPHN1

Research Areas for Latrophilin 1/LPHN1

Find related products by research area and learn more about each of the different research areas below.

Cancer
GPCR