Kir6.2 Products

Description

ATP-sensitive K+ channels play important roles in many cellular functions by coupling cell metabolism to electrical activity. KIR6.1 and KIR6.2 are members of the KIR (inwardly rectifying potassium channel) family of potassium channels. Inward rectifying K+ channels possess a greater tendency to allow potasium to flow into the cell rather than out of it. These channels comprise two subunits: a KIR6.0 subfamily component and a SUR component, which is a member of the ATP-binding cassette protein superfamily. Mutations in the gene coding for these channels are a cause of an autosomal recessive disorder characterized by unregulated insulin secretion. The amino-terminal and carboxyl-terminal domains of KIR channel subunits are both intracellular, and the two intracellular domains of KIR6.2 physically interact with each other.

Bioinformatics

Entrez	3767 Human 16514 Mouse
Uniprot	Q14654 Human
Product By Gene ID	3767
Alternate Names	ATP-sensitive inward rectifier potassium channel 11 beta-cell inward rectifier subunit BIRKIR6.2 HHF2 IKATP Inward rectifier K(+) channel Kir6.2 inwardly rectifying potassium channel KIR6.2 KCNJ11 Kir6.2 MGC133230 PHHI potassium channel inwardly rectifing subfamily J member 11 Potassium channel, inwardly rectifying subfamily J member 11 potassium inwardly-rectifying channel, subfamily J, member 11 TNDM3

Research Areas for Kir6.2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cardiovascular Biology
Neuroscience
Signal Transduction